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Issues raised in academic and consumer reviews include irritation in cosmetic-formulation use, very wide variation in product quality across the unregulated marketplace, formulation-stability problems, ingredient-interaction concerns, and a thin clinical-trial evidence base relative to the strength of consumer marketing claims

Their testimonials are, effectively, advertisements

By monitoring the inflammatory responses, such as cytokine secretion and receptor activation, various biomarkers can give us an indication of the possibility of a safe and efficient transport of copper through skin to exert its beneficial effects

Well-researched with decades of clinical data